Syndicated in newspapers worldwide and collected in sixteen books (and counting), this is the story of a girl and her unicorn. Or perhaps a unicorn and her girl. It's all about who you ask.
An internet strip that ran from 1998 to 2008, featuring two fox children and a menagerie of other characters. This strip, which still has a large following today, was recently republished in two books.
A political comic, initially in the Washington State University Daily Evergreen. It ran from 2004 to 2008, covering George W. Bush-era politics.